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Recombinant Human GDNF family receptor alpha-4 (GFRA4)

ACP24720

Number

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High Purity LevelsPrecision and ReliabilityCustomization Options

Main Attributes

Cat.No	ACP24720	Target Name	GFRA4
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	21-278	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9GZZ7

Background Information

Uniprot Id

Q9GZZ7
Target Species

Human
Target Name

GFRA4
Target Full Name

GDNF family receptor alpha-4
Target Function

Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.
Target Subcellular Location

[Isoform GFRalpha4a]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4b]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform GFRalpha4c]: Secreted.
Target Protein Families

GDNFR family
Target Tissue Specificity

Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands.
Target Synonyms

GDNF family receptor alpha 4; GDNF family receptor alpha-4; GDNF receptor alpha-4; GDNFR-alpha-4; GFR alpha 4; GFR receptor alpha 4; GFR-alpha-4; GFRA4; GFRA4_HUMAN; Glial cell line derived neurotrophic factor family receptor alpha 4; Neurotrophic factor receptor splice variant A (Gfra4 gene); OTTHUMP00000030106; OTTHUMP00000030107; Persephin receptor